A GENOME-WIDE RNAI SCREEN TO DISSECT CENTRIOLE DUPLICATION AND CENTROSOME MATURATION IN DROSOPHILA.

Centrosomes comprise a pair of centrioles surrounded by an amorphous pericentriolar material (PCM).Here, we have performed a microscopy-based genome-wide RNA interference (RNAi) screen in Drosophila cells to identify proteins required for centriole duplication and mitotic PCM Zinc recruitment.We analysed 92% of the Drosophila genome (13,059 genes)

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